HTH-01-015
HTH-01-015 is a potent and selective small molecule inhibitor of the NUAK1 kinase, demonstrating an IC50 of 100 nM. This compound is a valuable research tool for investigating NUAK1's role in cellular processes such as metabolism and autophagy, both in vitro and in animal models of related diseases.
Product Specifications
CAS Number
1613724-42-7
Product Name Alternative
AMP-activated protein kinase, AMPK, inhibit, NUAK1, NUAK2, HTH 01 015, HTH01015, HTH-01-015, Inhibitor
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
98.10% (May vary between batches)
Solubility
DMSO:52 mg/mL (110.98 mM) ; Ethanol:28 mg/mL (59.76 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.13 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CN1c2cc3ccccc3cc2C (=O) N (C) c2c (C) nc (Nc3cnn (c3) C3CCNCC3) nc12
Molecular Formula
C26H28N8O
Molecular Weight
468.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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