PLX-4032
Vemurafenib is a selective B-RAF inhibitor targeting the BRAF V600E mutation with potent antitumor activity. It is widely used in oncology research, demonstrating efficacy in both in vitro cellular assays and in vivo models of melanoma, supporting its clinical application for mutation-positive cancers.
Product Specifications
CAS Number
918504-65-1
Product Name Alternative
Vemurafenib; R7204; Ro 51-85426
Field of Research
Cell Biology
Purity
>98%
Bioactivity
B-Raf inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 100 mg/ml) .
Smiles
C (=O) (C=1C=2C (NC1) =NC=C (C2) C3=CC=C (Cl) C=C3) C4=C (F) C (NS (CCC) (=O) =O) =CC=C4F
Molecular Formula
C23H18ClF2N3O3S
Molecular Weight
489.92
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[3-[[5- (4-chlorophenyl) -1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
Available Sizes
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