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Panobinostat

Panobinostat (NVP-LBH589) is a potent, orally bioavailable, and non-selective HDAC inhibitor (IC50=5 nM) . It exhibits antitumor activity by inducing apoptosis and autophagy, making it a valuable tool for cancer research in both cellular and animal models.

Product Specifications

CAS Number

404950-80-7

Product Name Alternative

LBH-589

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

>98%

Bioactivity

HDAC inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming) .

Smiles

Cc1[nH]c2ccccc2c1CCNCc1ccc (\C=C\C (=O) NO) cc1

Molecular Formula

C21H23N3O2

Molecular Weight

349.44

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(E) -N-Hydroxy-3- (4- ((2- (2-methyl-1H-indol-3-yl) ethylamino) methyl) phenyl) acrylamide

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