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Pixantrone dimaleate

Pixantrone dimaleate, also known as BBR 2778, is a synthetic aza-anthracenedione investigational agent for research use. It functions as a DNA intercalator and topoisomerase II inhibitor, with demonstrated antitumor activity in both in vitro cell line studies and in vivo animal models of lymphoma and breast cancer.

Product Specifications

CAS Number

144675-97-8

Product Name Alternative

MDCK cell, intercalator, K562 cell, BBR 2778, BBR 2778 dimaleate, BBR2778, BBR-2778, BBR2778 Dimaleate, BBR-2778 Dimaleate, Topoisomerase, Pixantrone Maleate, Pixantrone, Pixantrone dimaleate

Field of Research

Molecular Biology, Pharmacology & Drug Discovery

Purity

98.51% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (1.79 mM) ; DMSO:91 mg/mL (163.31 mM)

Smiles

OC (=O) \C=C/C (O) =O.OC (=O) \C=C/C (O) =O.NCCNc1ccc (NCCN) c2C (=O) c3cnccc3C (=O) c12

Molecular Formula

C25H27N5O10

Molecular Weight

557.21

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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