Pixantrone dimaleate
Pixantrone dimaleate, also known as BBR 2778, is a synthetic aza-anthracenedione investigational agent for research use. It functions as a DNA intercalator and topoisomerase II inhibitor, with demonstrated antitumor activity in both in vitro cell line studies and in vivo animal models of lymphoma and breast cancer.
Product Specifications
CAS Number
144675-97-8
Product Name Alternative
MDCK cell, intercalator, K562 cell, BBR 2778, BBR 2778 dimaleate, BBR2778, BBR-2778, BBR2778 Dimaleate, BBR-2778 Dimaleate, Topoisomerase, Pixantrone Maleate, Pixantrone, Pixantrone dimaleate
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Purity
98.51% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (1.79 mM) ; DMSO:91 mg/mL (163.31 mM)
Smiles
OC (=O) \C=C/C (O) =O.OC (=O) \C=C/C (O) =O.NCCNc1ccc (NCCN) c2C (=O) c3cnccc3C (=O) c12
Molecular Formula
C25H27N5O10
Molecular Weight
557.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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