Candesartan Cilexetil
Candesartan Cilexetil is a prodrug hydrolyzed to the active AT1 receptor antagonist candesartan, which potently blocks angiotensin II-induced vasoconstriction (IC50: 0.26 nM) . It is widely used in research for studying hypertension, cardiovascular remodeling, and renal function in both in vitro receptor binding assays and in vivo animal models.
Product Specifications
CAS Number
145040-37-5
Product Name Alternative
Candesartan Cilexetil, Apoptosis, Angiotensin Receptor, angiotensin II receptor, Inhibitor, inhibit, TCV 116, TCV116, TCV-116
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
98.22% (May vary between batches)
Solubility
DMSO:250 mg/mL (409.39 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.28 mM)
Smiles
C (N1C=2C (N=C1OCC) =CC=CC2C (OC (OC (OC3CCCCC3) =O) C) =O) C4=CC=C (C=C4) C5=C (C=CC=C5) C=6NN=NN6
Molecular Formula
C33H34N6O6
Molecular Weight
610.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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