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Exisulind

Exisulind (CP248) is a pro-apoptotic small molecule that activates protein kinase G (PKG) . It demonstrates antineoplastic activity in vitro across various solid and hematological cancer cell lines and inhibits tumor growth in vivo in rodent models of colon, prostate, bladder, mammary, and lung cancers.

Product Specifications

CAS Number

59973-80-7

Product Name Alternative

Exisulind, Apoptosis, CP 248, CP248, CP-248, PKG, Sulindac sulfone

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

97.94% (May vary between batches)

Solubility

DMSO:55 mg/mL (147.69 mM)

Smiles

CC1=C (CC (O) =O) c2cc (F) ccc2\C1=C/c1ccc (cc1) S (C) (=O) =O

Molecular Formula

C20H17FO4S

Molecular Weight

372.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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