Exisulind
Exisulind (CP248) is a pro-apoptotic small molecule that activates protein kinase G (PKG) . It demonstrates antineoplastic activity in vitro across various solid and hematological cancer cell lines and inhibits tumor growth in vivo in rodent models of colon, prostate, bladder, mammary, and lung cancers.
Product Specifications
CAS Number
59973-80-7
Product Name Alternative
Exisulind, Apoptosis, CP 248, CP248, CP-248, PKG, Sulindac sulfone
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.94% (May vary between batches)
Solubility
DMSO:55 mg/mL (147.69 mM)
Smiles
CC1=C (CC (O) =O) c2cc (F) ccc2\C1=C/c1ccc (cc1) S (C) (=O) =O
Molecular Formula
C20H17FO4S
Molecular Weight
372.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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