PP242
PP 242 (Torkinib) is a potent, ATP-competitive inhibitor of mTOR with an IC50 of 8 nM, effectively targeting both mTORC1 and mTORC2 complexes. It is widely used in preclinical research to study mTOR signaling in cancer biology, utilizing both cellular assays and in vivo models to investigate proliferation and survival pathways.
Product Specifications
CAS Number
1092351-67-1
Product Name Alternative
Torkinib
Field of Research
Cancer Biology, Neuroscience
Purity
>98%
Bioactivity
MTOR kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 8 mg/ml)
Smiles
CC (C) n1nc (-c2cc3cc (O) ccc3[nH]2) c2c (N) ncnc12
Molecular Formula
C16H16N6O
Molecular Weight
308.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-[4-Amino-1- (1-methylethyl) -1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol
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