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PP242

PP 242 (Torkinib) is a potent, ATP-competitive inhibitor of mTOR with an IC50 of 8 nM, effectively targeting both mTORC1 and mTORC2 complexes. It is widely used in preclinical research to study mTOR signaling in cancer biology, utilizing both cellular assays and in vivo models to investigate proliferation and survival pathways.

Product Specifications

CAS Number

1092351-67-1

Product Name Alternative

Torkinib

Field of Research

Cancer Biology, Neuroscience

Purity

>98%

Bioactivity

MTOR kinase inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 8 mg/ml)

Smiles

CC (C) n1nc (-c2cc3cc (O) ccc3[nH]2) c2c (N) ncnc12

Molecular Formula

C16H16N6O

Molecular Weight

308.3

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

2-[4-Amino-1- (1-methylethyl) -1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol

Available Sizes

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