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(E/Z) -BIX 02189

(E/Z) -BIX 02189 is a stereoisomer of the MEK5 inhibitor BIX 02189. This chemical probe is utilized in biochemical studies to investigate the ERK5 signaling pathway in both cellular and enzymatic assays.

Product Specifications

CAS Number

1094614-85-3

Product Name Alternative

BIX 02189, BIX02189, BIX-02189, MEK1, MEK2, MEK5, ERK5, TGFbeta/Smad, TGF-beta, TGFb, TGF-b/Smad, TGFbeta, Smad, TGFβR1, TGFβ, TGF-β/Smad

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

98.00% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:74 mg/mL (167.98 mM) ; DMSO:22.73 mg/mL (51.6 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.54 mM)

Smiles

C (NC1=CC (CN (C) C) =CC=C1) (=C2C=3C (NC2=O) =CC (C (N (C) C) =O) =CC3) C4=CC=CC=C4

Molecular Formula

C27H28N4O2

Molecular Weight

440.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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