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JTV-519

JTV-519 is a calcium-stabilizing agent that inhibits pathological Ca2+ leakage from the sarcoplasmic reticulum by targeting ryanodine receptors. It is widely used in cardiovascular and muscular disease research, with applications in both in vitro assays and in vivo models of ischemia and heart failure.

Product Specifications

CAS Number

1038410-88-6

Product Name Alternative

K201, K-201, JTV519, JTV-519, JTV 519, K 201, CalciumChannel, Ca (2+) receptor, Calcium Channel

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

99.80% (May vary between batches)

Solubility

DMSO:25 mg/mL (54.22 mM)

Smiles

Cl.O=C (N1CC2=CC (OC) =CC=C2SCC1) CCN3CCC (CC=4C=CC=CC4) CC3

Molecular Formula

C25H33ClN2O2S

Molecular Weight

461.06

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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