P22077
P 22077 is a small molecule inhibitor of the deubiquitinase USP7 (UniProt ID P22077) with an EC50 of 8.6 μM, and it also potently targets USP47. This compound is a valuable research tool for probing the roles of these enzymes in cellular processes such as the p53 pathway, DNA damage response, and Wnt signaling, both in vitro and in vivo.
Product Specifications
CAS Number
1247819-59-5
Product Name Alternative
Deubiquitinase, DUBs, Inhibitor, inhibit, USP2, USP7, USP4, USP47, USP5, P22077, P-22077, P 22077
Field of Research
Cell Biology, Protein Biochemistry
Purity
>98%
Bioactivity
USP7 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
CC (=O) c1cc (c (Sc2ccc (F) cc2F) s1) [N+] ([O-]) =O
Molecular Formula
C12H7F2NO3S2
Molecular Weight
315.32
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1- (5- ((2,4-Difluorophenyl) thio) -4-nitrothiophen-2-yl) ethanone
Available Sizes
Frequently Asked Questions
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