KPT185
KPT-185 is a potent and selective inhibitor of CRM1 (exportin 1) . It induces cell-cycle arrest and apoptosis, making it a valuable tool for studying nuclear export in cancer research, both in vitro and in vivo models.
Product Specifications
CAS Number
1333151-73-7
Product Name Alternative
KPT 185, KPT185, KPT-185, CRM1
Field of Research
Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
Ethanol:66 mg/mL (185.75 mM) ; DMSO:66 mg/mL (185.75 mM) ; H2O:<1 mg/mL
Smiles
COc1cc (cc (c1) C (F) (F) F) -c1ncn (C=CC (=O) OC (C) C) n1
Molecular Formula
C16H16F3N3O3
Molecular Weight
355.31
Storage Conditions
-20°C
Notes
For research use only.
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