KPT-251
KPT-251 is a small molecule that potently and selectively inhibits nuclear export. It is utilized in cancer research, particularly in studies of leukemia and solid tumors, to investigate the biological consequences of XPO1 inhibition in both cellular and animal models.
Product Specifications
CAS Number
1388841-50-6
Product Name Alternative
A375, antileukemic activity, Apoptosis, CRM1, Chromosomal Maintenance 1, KPT 251, KPT251, KPT-251, myeloid leukemia, inhibit, nuclear export, Inhibitor, melanoma, Exportin 1, XPO1
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.54% (May vary between batches)
Solubility
DMSO:65 mg/mL (173.23 mM)
Smiles
C (F) (F) (F) C=1C=C (C=C (C (F) (F) F) C1) C2=NN (/C=C\C3=NN=CO3) C=N2
Molecular Formula
C14H7F6N5O
Molecular Weight
375.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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