Ki8751
KI8751 is a highly potent and selective small molecule inhibitor targeting VEGFR2, demonstrating an IC50 value of 0.9 nM. It is widely used in preclinical research to study angiogenesis, tumor growth, and metastasis in both cellular assays and animal models.
Product Specifications
CAS Number
228559-41-9
Product Name Alternative
C-Kit, cKit, inhibit, Inhibitor, KI8751, KI-8751, KI 8751, Ki 8751, EGFR, FGFR2, PDGFRα, Vascular endothelial growth factor receptor, VEGFR2, VEGFR
Field of Research
Cardiovascular Research
Purity
>98%
Bioactivity
VEGFR2 inhibitor (potent)
Form
Powder
Solubility
Soluble in DMSO (up to 15 mg/ml)
Smiles
COc1cc2nccc (Oc3ccc (NC (=O) Nc4ccc (F) cc4F) c (F) c3) c2cc1OC
Molecular Formula
C24H18F3N3O4
Molecular Weight
469.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N- (2,4-difluorophenyl) -N'-[4-[ (6,7-dimethoxy-4-quinolinyl) oxy]-2-fluorophenyl]-urea
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