C-646
C646 is a potent, selective, and competitive inhibitor of the histone acetyltransferase p300 (Ki=400 nM) . It functions as an apoptosis inducer and radiosensitizer, with research applications in oncology for studying epigenetic mechanisms in both cellular and animal models.
Product Specifications
CAS Number
328968-36-1
Product Name Alternative
EpigeneticReaderDomain, Epigenetic Reader Domain, HistoneAcetyltransferase, Histone Acetyltransferase, HATs, HAT, inhibit, Inhibitor, C646, C-646, C 646, Autophagy, Apoptosis, p300/CBP
Field of Research
Cell Biology, Epigenetics & Chromatin, Neuroscience
Purity
>98%
Bioactivity
HAT inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 10 mg/ml) .
Smiles
CC1=NN (C (=O) C1=Cc1ccc (o1) -c1cc (C) c (C) cc1[N+] ([O-]) =O) c1ccc (cc1) C (O) =O
Molecular Formula
C24H19N3O6
Molecular Weight
445.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4-[4-[[5- (4,5-Dimethyl-2-nitrophenyl) -2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid
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