BRL 54443
BRL 54443 is a selective and high-affinity agonist for the 5-HT1E and 5-HT1F receptors, with pKi values of 8.7 and 8.9, respectively. It is a valuable research tool for investigating serotonin receptor function in models of migraine and neuropathic pain, both in vitro and in vivo.
Product Specifications
CAS Number
57477-39-1
Product Name Alternative
BRL 54443, BRL54443, BRL-54443, 5-hydroxytryptamine Receptor, 5HTReceptor, 5HT Receptor, 5-HT Receptor, 5-HT1E, 5-HT1F, 5-HT1D, 5-HT1B, 5-HT1A, Inhibitor, inhibit, Serotonin Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.07% (May vary between batches)
Solubility
DMSO:43 mg/mL (186.7 mM) ; Ethanol:2 mg/mL (8.68 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.68 mM)
Smiles
OC=1C=C2C (=CNC2=CC1) C3CCN (C) CC3
Molecular Formula
C14H18N2O
Molecular Weight
230.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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