PIK-90
PIK-90 is a potent dual inhibitor of DNA-PK and PI3K, demonstrating nanomolar IC50 values against p110α (11 nM), p110γ (18 nM), and DNA-PK (13 nM) . This small molecule is a valuable research tool for investigating DNA damage response and PI3K signaling pathways in both cellular and biochemical assays.
Product Specifications
CAS Number
677338-12-4
Product Name Alternative
Inhibit, Inhibitor, DNA-dependent protein kinase, DNA-PK, DNAPK, Phosphoinositide 3-kinase, PI3K, PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, PIK 90, PIK90, PIK-90
Field of Research
Molecular Biology, Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
H2O:< 0.2 mg/mL (insoluble or slightly soluble) ; Ethanol:< 0.2 mg/mL (insoluble or slightly soluble) ; DMSO:< 0.2 mg/mL (insoluble or slightly soluble)
Smiles
COc1ccc2C3=NCCN3C (NC (=O) c3cccnc3) =Nc2c1OC
Molecular Formula
C18H17N5O3
Molecular Weight
351.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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