PF-249
PF-249 (PF-06685249) is a potent and β1-selective AMPK activator, demonstrating an EC50 of 12 nM for the α1β1γ1 isoform. This small molecule is a valuable research tool for investigating metabolic diseases, including studies on diabetic nephropathy in both cellular and animal models.
Product Specifications
CAS Number
1467059-70-6
Product Name Alternative
AMPK α1β1γ1, PF 249, PF 06685249, PF06685249, PF-06685249, PF249, PF-249
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
97.01% (May vary between batches)
Solubility
DMSO:90 mg/mL (260.28 mM)
Smiles
COc1nc (ccc1-c1cc2c (c[nH]c2cc1Cl) C (O) =O) N (C) C
Molecular Formula
C17H16ClN3O3
Molecular Weight
345.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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