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PF-249

PF-249 (PF-06685249) is a potent and β1-selective AMPK activator, demonstrating an EC50 of 12 nM for the α1β1γ1 isoform. This small molecule is a valuable research tool for investigating metabolic diseases, including studies on diabetic nephropathy in both cellular and animal models.

Product Specifications

CAS Number

1467059-70-6

Product Name Alternative

AMPK α1β1γ1, PF 249, PF 06685249, PF06685249, PF-06685249, PF249, PF-249

Field of Research

Epigenetics & Chromatin, Signal Transduction

Purity

97.01% (May vary between batches)

Solubility

DMSO:90 mg/mL (260.28 mM)

Smiles

COc1nc (ccc1-c1cc2c (c[nH]c2cc1Cl) C (O) =O) N (C) C

Molecular Formula

C17H16ClN3O3

Molecular Weight

345.78

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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