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PQ-10

PQ-10 (A-844337) is a selective phosphodiesterase 10A (PDE10A) inhibitor used in neuroscience research. It modulates striatal circuitry and alters cerebral glucose metabolism, serving as a potential translational biomarker in studies of psychiatric and neurological disorders, including in vivo models of Huntington's disease.

Product Specifications

CAS Number

927691-21-2

Product Name Alternative

A 844337, A844337, A-844337, glucose metabolism, Inhibitor, inhibit, PDE10A, psychiatric disorders, schizophrenia, Phosphodiesterase (PDE), Phosphodiesterase 10A, PQ 10, PQ10, PQ-10, translational biomarker

Field of Research

Metabolism Research

Purity

99.30% (May vary between batches)

Solubility

DMSO:60 mg/mL (148.72 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.96 mM)

Smiles

COc1cc2ncnc (N3CCC (C3) Oc3cnc4ccccc4n3) c2cc1OC

Molecular Formula

C22H21N5O3

Molecular Weight

403.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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