R406 free base
R406 free base is a selective and potent inhibitor of spleen tyrosine kinase (Syk) . It is widely used in biochemical and cellular research to investigate Syk-dependent signaling pathways in immunology and oncology, with applications in both in vitro assays and in vivo disease models.
Product Specifications
CAS Number
841290-80-0
Product Name Alternative
Inhibitor, inhibit, FLT3, Fms like tyrosine kinase 3, Apoptosis, Cluster of differentiation antigen 135, CD135, Spleen tyrosine kinase, Syk, R406, R-406, R406 (free base), R406 free base, R-406 free base, R 406
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
97.12% (May vary between batches)
Solubility
DMSO:4.71 mg/mL (10.01 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
COc1cc (Nc2ncc (F) c (Nc3ccc4OC (C) (C) C (=O) Nc4n3) n2) cc (OC) c1OC
Molecular Formula
C22H23FN6O5
Molecular Weight
470.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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