FK-866 HCl
FK866 (Daporinad) is a potent and specific non-competitive inhibitor of NAMPT with an IC50 of 0.09 nM. It is widely used in oncology research to study NAD+ depletion, demonstrating anti-proliferative effects in vitro and anti-tumor activity in various xenograft models.
Product Specifications
CAS Number
658084-64-1
Product Name Alternative
Daporinad, Autophagy, APO866, APO-866, APO 866, (E) Daporinad, (E) -N-[4- (1-BENZOYL-PIPERIDIN-4-YL) -BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE, (E) Daporinad, (E) -Daporinad, inhibit, NMPRTase, Nicotinamide phosphoribosyl transferase, PBEF, NAMPT, FK866, FK-866, FK 866, Inhibitor, Pre-B cell colony enhancing factor, Visfatin
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
>98%
Bioactivity
NAD biosynthesis inhibitor
Form
Powder
Solubility
Soluble in Water (up to 40 mg/ml) .
Smiles
C (=O) (N1CCC (CCCCNC (/C=C/C=2C=CC=NC2) =O) CC1) C3=CC=CC=C3
Molecular Formula
C24H29N3O2 ∙ HCl
Molecular Weight
428.0
Storage Conditions
-20°C (hygroscopic)
Notes
For research use only.
Available Sizes
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