Menin-MLL inhibitor MI-2
MI-2 (MI2) is a small molecule inhibitor that potently disrupts the menin-MLL protein interaction with an IC50 of 446 nM. It is a valuable research tool for studying MLL-rearranged leukemias in both cellular and animal models, aiding in the exploration of targeted therapeutic strategies.
Product Specifications
CAS Number
1271738-62-5
Product Name Alternative
Apoptosis, Menin MLL inhibitor MI 2, Menin-MLL, MeninMLL inhibitor MI2, Menin-MLL inhibitor MI-2, MI2, MI-2, MI 2, Menin-MLL Inhibitor, Menin-MLL inhibitor 2, Histone Methyltransferase, HistoneMethyltransferase, EpigeneticReaderDomain, Epigenetic Reader Domain
Field of Research
Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Pharmacology & Drug Discovery
Purity
97.46% (May vary between batches)
Solubility
Ethanol:70 mg/mL (186.39 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:70 mg/mL (186.39 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.33 mM)
Smiles
CCCc1cc2c (ncnc2s1) N1CCN (CC1) C1=NCC (C) (C) S1
Molecular Formula
C18H25N5S2
Molecular Weight
375.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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