GW-2580
GW2580 (SC-203877) is an orally bioavailable, selective inhibitor of the CSF-1R (c-FMS) tyrosine kinase. It is widely used in preclinical research to investigate the role of tumor-associated macrophages in cancer models and to study inflammatory diseases in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
870483-87-7
Product Name Alternative
SC 203877, SC203877, SC-203877, CSF1R, CSF-1R, CSF-1 receptor, colony stimulating factor 1 receptor, c-Fms, cFms, inhibit, GW 2580, GW2580, GW-2580, Inhibitor
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
CFMS kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml) .
Smiles
COc1ccc (COc2ccc (Cc3cnc (N) nc3N) cc2OC) cc1
Molecular Formula
C20H22N4O3
Molecular Weight
366.32
Storage Conditions
RT
Notes
For research use only.
Other Product Names
5- (3-Methoxy-4- ((4-methoxybenzyl) oxy) benzyl) pyrimidine-2,4-diamine
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
T8665-23D1-FITC 100 µL
Troponin T, Cardiac (cTnT, TnTc, Cardiac muscle troponin T, TNNT2) (FITC) discontinued
Sign In for Pricing
View Details 
orb1948457-01 48 Tests
Mouse Glucocorticoid Receptor Alpha (GRα) ELISA Kit
Sign In for Pricing
View Details orb1948457-02 96 Tests
Mouse Glucocorticoid Receptor Alpha (GRα) ELISA Kit
Sign In for Pricing
View Details MBS7202519-01 48 Well
Rat Charged multivesicular body protein 2a (CHMP2A) ELISA Kit
Sign In for Pricing
View Details MBS7202519-02 96 Well
Rat Charged multivesicular body protein 2a (CHMP2A) ELISA Kit
Sign In for Pricing
View Details