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GW-2580

GW2580 (SC-203877) is an orally bioavailable, selective inhibitor of the CSF-1R (c-FMS) tyrosine kinase. It is widely used in preclinical research to investigate the role of tumor-associated macrophages in cancer models and to study inflammatory diseases in both in vitro and in vivo experimental settings.

Product Specifications

CAS Number

870483-87-7

Product Name Alternative

SC 203877, SC203877, SC-203877, CSF1R, CSF-1R, CSF-1 receptor, colony stimulating factor 1 receptor, c-Fms, cFms, inhibit, GW 2580, GW2580, GW-2580, Inhibitor

Field of Research

Immunology & Inflammation

Purity

>98%

Bioactivity

CFMS kinase inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 40 mg/ml) .

Smiles

COc1ccc (COc2ccc (Cc3cnc (N) nc3N) cc2OC) cc1

Molecular Formula

C20H22N4O3

Molecular Weight

366.32

Storage Conditions

RT

Notes

For research use only.

Other Product Names

5- (3-Methoxy-4- ((4-methoxybenzyl) oxy) benzyl) pyrimidine-2,4-diamine

Available Sizes

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