PIK-75
PIK-75 is a potent dual inhibitor of DNA-PK and PI3K, exhibiting low nanomolar IC50 values against DNA-PK (2 nM) and p110α (5.8 nM), with additional activity against p110γ (76 nM) . This small molecule is a valuable research tool for investigating DNA damage response and PI3K signaling pathways in both cellular and biochemical assays.
Product Specifications
CAS Number
372196-67-3
Product Name Alternative
DNA-dependent protein kinase, DNAPK, DNA-PK, cells, CHO-IR, apoptotic, Apoptosis, cancer, pancreatic, inhibit, Inhibitor, PKB, PI3K, Phosphoinositide 3-kinase, PIK 75, PIK75, PIK-75, p110α, p110β, p110γ, p110δ
Field of Research
Cell Biology, Molecular Biology, Signal Transduction
Purity
98.19% (May vary between batches)
Solubility
DMSO:4.53 mg/mL (10.02 mM)
Smiles
CN (\N=C\c1cnc2ccc (Br) cn12) S (=O) (=O) c1cc (ccc1C) [N+] ([O-]) =O
Molecular Formula
C16H14BrN5O4S
Molecular Weight
452.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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