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PF-04217903

PF-04217903 is an orally bioavailable, small-molecule inhibitor targeting the MET tyrosine kinase, exhibiting antineoplastic potential. It has been utilized in preclinical research to investigate MET-driven oncogenesis, demonstrating activity in both in vitro cellular assays and in vivo tumor models.

Product Specifications

CAS Number

956905-27-4

Product Name Alternative

Phosphorylation, phospho-PDGFRβ, PF 04217903, PF04217903, PF-04217903, colon, c-Met/HGFR, c-Met, cMet/HGFR, cMet, carcinoma, inhibit, migration, lung, Inhibitor, HGFR, gastric, GTL-16

Field of Research

Signal Transduction

Purity

98.41% (May vary between batches)

Solubility

DMSO:20 mg/mL (53.71 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+90% Corn Oil:2 mg/mL (5.37 mM)

Smiles

OCCn1cc (cn1) -c1cnc2nnn (Cc3ccc4ncccc4c3) c2n1

Molecular Formula

C19H16N8O

Molecular Weight

372.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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