PF-04217903
PF-04217903 is an orally bioavailable, small-molecule inhibitor targeting the MET tyrosine kinase, exhibiting antineoplastic potential. It has been utilized in preclinical research to investigate MET-driven oncogenesis, demonstrating activity in both in vitro cellular assays and in vivo tumor models.
Product Specifications
CAS Number
956905-27-4
Product Name Alternative
Phosphorylation, phospho-PDGFRβ, PF 04217903, PF04217903, PF-04217903, colon, c-Met/HGFR, c-Met, cMet/HGFR, cMet, carcinoma, inhibit, migration, lung, Inhibitor, HGFR, gastric, GTL-16
Field of Research
Signal Transduction
Purity
98.41% (May vary between batches)
Solubility
DMSO:20 mg/mL (53.71 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+90% Corn Oil:2 mg/mL (5.37 mM)
Smiles
OCCn1cc (cn1) -c1cnc2nnn (Cc3ccc4ncccc4c3) c2n1
Molecular Formula
C19H16N8O
Molecular Weight
372.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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