BMS-8
BMS-8 is a small molecule PD-1/PD-L1 interaction inhibitor with an IC50 of 7.2 μM. It functions by binding to PD-L1 and promoting its homodimerization. This mechanism supports its application in cancer immunotherapy research, including in vitro assays to study immune checkpoint blockade.
Product Specifications
CAS Number
1675201-90-7
Product Name Alternative
PPI, PD-L1, PDL1, inhibit, PD-1/PD-L1, PD1/PDL1, PD-1, PD1, Inhibitor, BMS 8, BMS8, BMS-8
Field of Research
Cell Biology, Immunology & Inflammation
Purity
98.88% (May vary between batches)
Solubility
DMSO:15.31 mg/mL (30.97 mM)
Smiles
Cc1c (COc2ccc (CN3CCCCC3C (O) =O) cc2Br) cccc1-c1ccccc1
Molecular Formula
C27H28BrNO3
Molecular Weight
494.42
Storage Conditions
-20°C
Notes
For research use only.
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