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BMS-986122

BMS-986122 is a μ-opioid receptor positive allosteric modulator. In vitro, it potentiates endomorphin-1-stimulated β-arrestin recruitment in OPRM1-expressing cells with an EC50 of 3 μM. This compound is a research tool for studying biased signaling and allosteric modulation in opioid receptor pharmacology.

Product Specifications

CAS Number

313669-88-4

Product Name Alternative

Protein, positive, recruitment, β-arrestin, BMS 986122, BMS986122, BMS-986122, allosteric, adenylyl, cyclase, inhibit, Opioid Receptor, OpioidReceptor, modulator, Inhibitor

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

98.42% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:3.3 mg/mL (7.35 mM) ; DMSO:100 mg/mL (222.83 mM)

Smiles

COc1ccc (cc1Br) C1SCCN1S (=O) (=O) c1ccc (Cl) cc1

Molecular Formula

C16H15BrClNO3S2

Molecular Weight

448.78

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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