AZ3146
AZ3146 is a potent and selective small molecule inhibitor of the Mps1 kinase, demonstrating an IC50 of approximately 35 nM. It is widely used in biochemical and cellular research to study mitotic checkpoint signaling and has been employed in both in vitro assays and in vivo xenograft models to investigate its potential in oncology.
Product Specifications
CAS Number
1124329-14-1
Product Name Alternative
AZ 3146, AZ3146, AZ-3146, inhibit, Mps1, Inhibitor, Monopolar spindle 1
Field of Research
Signal Transduction
Purity
>98%
Bioactivity
Msp1 kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to at least 25 mg/ml)
Smiles
O=C1N (C=2C (N1C) =CN=C (NC3=C (OC) C=C (OC4CCN (C) CC4) C=C3) N2) C5CCCC5
Molecular Formula
C24H32N6O3S2
Molecular Weight
452.56
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
9-Cyclopentyl-2-[2-methoxy-4- (1-methylpiperidine-4-yl) oxyanilino]-7-methylpurin-8-one
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