KN-93
KN-93 is a cell-permeable, selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII) that acts by competitively antagonizing calmodulin binding. It is widely used in vitro and in vivo to investigate CaMKII's roles in cardiac function, neuronal signaling, and synaptic plasticity.
Product Specifications
CAS Number
139298-40-1
Product Name Alternative
Autophagy, CaMK, Calmodulin-dependent protein kinases, Calmodulin-dependent kinases, Inhibitor, inhibit, KN93, KN-93, KN 93
Field of Research
Cell Biology, Neuroscience
Purity
99.56% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:1 mg/mL (2 mM) ; DMSO:50 mg/mL (99.79 mM)
Smiles
N (S (=O) (=O) C1=CC=C (OC) C=C1) (CCO) C2=C (CN (CC=CC3=CC=C (Cl) C=C3) C) C=CC=C2
Molecular Formula
C26H29ClN2O4S
Molecular Weight
501.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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