BMS 777607
BMS-777607 is a potent small molecule inhibitor targeting the receptor tyrosine kinases c-Met, Axl, Ron, and Tyro3. It has demonstrated activity in preclinical research, including in vitro cell-based assays and in vivo xenograft models, for studying various solid tumors.
Product Specifications
CAS Number
1025720-94-8
Product Name Alternative
BMS 777607, BMS 817378, BMS777607, BMS-777607, BMS817378, BMS-817378, AXL, Axl, cMet, c-Met, c-Met/HGFR, cMet/HGFR, Mer, HGFR, Met, Inhibitor, inhibit, RON, TAMReceptor, TAM Receptor, Tyro3
Field of Research
Signal Transduction
Purity
98.30% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.9 mM) ; DMSO:44 mg/mL (85.79 mM)
Smiles
CCOc1ccn (-c2ccc (F) cc2) c (=O) c1C (=O) Nc1ccc (Oc2ccnc (N) c2Cl) c (F) c1
Molecular Formula
C25H19ClF2N4O4
Molecular Weight
512.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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