MLN0905
MLN0905 is a potent and selective small molecule inhibitor of PLK1 with an IC50 of 2 nM. It is a valuable research tool for studying mitosis and cell cycle progression in vitro and has demonstrated antitumor activity in preclinical in vivo cancer models.
Product Specifications
CAS Number
1228960-69-7
Product Name Alternative
Inhibitor, inhibit, MLN0905, MLN-0905, MLN 0905, PLK, PLK1, PLK1 Inhibitor, Polo-like Kinase (PLK)
Field of Research
Cell Biology
Purity
97.17% (May vary between batches)
Solubility
DMSO:90 mg/mL (184.97 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.78 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CN (C) CCCc1cnc (C) c (Nc2ncc3CC (=S) Nc4cc (ccc4-c3n2) C (F) (F) F) c1
Molecular Formula
C24H25F3N6S
Molecular Weight
486.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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