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MLN0905

MLN0905 is a potent and selective small molecule inhibitor of PLK1 with an IC50 of 2 nM. It is a valuable research tool for studying mitosis and cell cycle progression in vitro and has demonstrated antitumor activity in preclinical in vivo cancer models.

Product Specifications

CAS Number

1228960-69-7

Product Name Alternative

Inhibitor, inhibit, MLN0905, MLN-0905, MLN 0905, PLK, PLK1, PLK1 Inhibitor, Polo-like Kinase (PLK)

Field of Research

Cell Biology

Purity

97.17% (May vary between batches)

Solubility

DMSO:90 mg/mL (184.97 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.78 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CN (C) CCCc1cnc (C) c (Nc2ncc3CC (=S) Nc4cc (ccc4-c3n2) C (F) (F) F) c1

Molecular Formula

C24H25F3N6S

Molecular Weight

486.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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