SL327
SL327 is a potent and selective MEK1/2 inhibitor with IC50 values of 0.18 μM and 0.22 μM, respectively. Its ability to cross the blood-brain barrier makes it a valuable tool for investigating the MAPK/ERK pathway in both cellular assays and in vivo models of neurological diseases.
Product Specifications
CAS Number
305350-87-2
Product Name Alternative
SL327, SL-327, SL 327, RNA Synthesis, RNASynthesis, inhibit, Mitogen-activated protein kinase kinase, Inhibitor, MAPKK, MAP2K, MEK, MEK2, MEK1, DNA Synthesis, DNASynthesis, AP-1
Field of Research
Cell Biology, Molecular Biology, Signal Transduction
Purity
97.98% (May vary between batches)
Solubility
Ethanol:16.8 mg/mL (50.1 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.96 mM) ; DMSO:50 mg/mL (149.1 mM)
Smiles
NC (Sc1ccc (N) cc1) =C (C#N) c1ccccc1C (F) (F) F
Molecular Formula
C16H12F3N3S
Molecular Weight
335.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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