Crisdesalazine
Crisdesalazine (AAD 2004) is a selective mPGES-1 inhibitor. It has demonstrated neuroprotective effects in research models, reducing autophagosome formation, axonopathy, and motor neuron degeneration, which correlates with improved motor function and extended survival in vivo.
Product Specifications
CAS Number
927685-43-6
Product Name Alternative
Crisdesalazine, AAD2004, AAD-2004, AAD 2004, mPGES-1, Prostaglandin Receptor, ProstaglandinReceptor
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
95.95% (May vary between batches)
Solubility
DMSO:3.26 mg/mL (10.02 mM)
Smiles
OC (=O) c1cc (NCCc2ccc (cc2) C (F) (F) F) ccc1O
Molecular Formula
C16H14F3NO3
Molecular Weight
325.28
Storage Conditions
-20°C
Notes
For research use only.
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