TCS 1102
TCS 1102 is a potent dual orexin receptor antagonist with high affinity for OX2 (Ki=0.2 nM) and OX1 (Ki=3 nM) receptors. It is a valuable research tool for studying sleep-wake regulation and is used in both in vitro binding assays and in vivo models of insomnia.
Product Specifications
CAS Number
916141-36-1
Product Name Alternative
Fear, hypocretin, Hypocretin Receptor, Inhibitor, HCRT Receptor, inhibit, orexin, Orexin Receptor (OX Receptor), anxiety, DORA-1, central activity, OX2, OX1, OX Receptor, OXReceptor, post-traumatic stress disorder, pharmacodynamic model, T-maze, TCS 1102, TCS-1102, TCS1102
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.35% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.25 mM) ; DMSO:50 mg/mL (106.25 mM) ; Ethanol:100 mM
Smiles
Cn1c (SCC (=O) N2CCC[C@@H]2C (=O) Nc2ccccc2-c2ccccc2) nc2ccccc12
Molecular Formula
C27H26N4O2S
Molecular Weight
470.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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