Chembridge-5861528
Chembridge-5861528 is a selective TRPA1 channel antagonist, inhibiting calcium influx evoked by AITC and 4-HNE with IC50 values of 14.3 μM and 18.7 μM, respectively. This compound is a valuable research tool for studying TRPA1-mediated pathways in pain, inflammation, and respiratory disorders in both cellular and animal models.
Product Specifications
CAS Number
332117-28-9
Product Name Alternative
Antihypersensitivity, diabetes mellitus, Chembridge 5861528, Chembridge5861528, Chembridge-5861528, inhibit, neurogenic inflammation, Inhibitor, TCS 5861528, TCS-5861528, TCS5861528, Transient receptor potential channels, TRPChannel, TRPA1, TRP Channel, TRPV Channel, TRPVChannel
Field of Research
Pharmacology & Drug Discovery
Purity
99.97% (May vary between batches)
Solubility
DMSO:50 mg/mL (135.35 mM)
Smiles
CCC (C) c1ccc (NC (=O) Cn2cnc3n (C) c (=O) n (C) c (=O) c23) cc1
Molecular Formula
C19H23N5O3
Molecular Weight
369.42
Storage Conditions
-20°C
Notes
For research use only.
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