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Sinomenine

Sinomenine (Kukoline) is an alkaloid derived from Sinomenium acutum, studied for its potential in rheumatism and arthritis research. In vitro and in vivo studies indicate it possesses anti-inflammatory and immunomodulatory properties relevant to autoimmune disease models.

Product Specifications

CAS Number

115-53-7

Product Name Alternative

Cucoline, Autophagy, Apoptosis, Inhibitor, inhibit, Kukoline, NF-kB, NFκB, NFkB, NF-κB, Nuclear factor-kappaB, Nuclear factor-κB, Opioid Receptor, OpioidReceptor, Sinomenine

Field of Research

Cell Biology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.02% (May vary between batches)

Solubility

DMSO:148 mg/mL (449.32 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.14 mM) ; H2O:10 mg/mL (30.36 mM)

Smiles

COC1=C[C@@H]2[C@@H]3Cc4ccc (OC) c (O) c4[C@]2 (CCN3C) CC1=O

Molecular Formula

C19H23NO4

Molecular Weight

329.39

Storage Conditions

-20°C

Notes

For research use only.

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