GSK3987
GSK3987 is a synthetic ligand for Liver X Receptors (LXRα and LXRβ), demonstrating potent agonist activity by recruiting the steroid receptor coactivator-1 with EC50 values of 40 nM. This small molecule is a valuable research tool for studying LXR-mediated pathways in lipid metabolism, inflammation, and atherosclerosis in both cellular and animal models.
Product Specifications
CAS Number
264206-85-1
Product Name Alternative
LXR, LXRβ, LXRα, LiverXReceptor, Liver X receptor, Liver X Receptor, inhibit, macrophages, GSK3987, GSK-3987, GSK 3987, Inhibitor, HepG2 cells, ABCA1, cellular cholesterol, SREBP-1c, triglyceride accumulation
Field of Research
Metabolism Research
Purity
99.48% (May vary between batches)
Solubility
DMSO:50 mg/mL (130.06 mM)
Smiles
COc1ccc (NC2=C (C (=O) N (Cc3ccccc3) C2=O) c2ccccc2) cc1
Molecular Formula
C24H20N2O3
Molecular Weight
384.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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