(S) -10-Hydroxycamptothecin
(S) -10-Hydroxycamptothecin (10-HCPT) is a potent topoisomerase I inhibitor used in cancer research. It demonstrates significant antitumor activity in both in vitro cell assays and in vivo models, particularly in studies focused on hepatoma and other solid tumors.
Product Specifications
CAS Number
19685-09-7
Product Name Alternative
PCNA, p53, G2/M, Cell-cycle, c-Myc, (S) 10 Hydroxycamptothecin, 10-HCPT, 10-Hydroxycamptothecin, (S) 10Hydroxycamptothecin, caspase-1/3r, Bcl-2, Apoptosis, antitumor, arrest, Bax, Topoisomerase, Topo I
Field of Research
Cell Biology, Molecular Biology
Purity
99.09% (May vary between batches)
Solubility
DMSO:26 mg/mL (71.36 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
O=C1N2C (C=3C (C2) =CC=4C (N3) =CC=C (O) C4) =CC5=C1COC (=O) [C@@]5 (CC) O
Molecular Formula
C20H16N2O5
Molecular Weight
364.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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