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Saikosaponin A

Saikosaponin A is a bioactive small molecule with broad pharmacological activities, including neuroprotective, anti-inflammatory, and immunomodulatory effects. Research demonstrates its efficacy in attenuating neuropathic pain in CCI rat models by inhibiting spinal p38 MAPK/NF-κB pathways, NMDA currents, and pro-inflammatory cytokine production, supporting its use in neuroscience and immunology research.

Product Specifications

CAS Number

20736-09-8

Product Name Alternative

Saikosaponin A, NF-κB, NFκB, NFkB, NF-kB, LXR, inhibit, Liver X receptor, Liver X Receptor, LiverXReceptor, Inhibitor, Bacterial

Field of Research

Infectious Disease & Virology, Metabolism Research, Signal Transduction

Purity

98.76% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.56 mM) ; H2O:Insoluble; DMSO:50 mg/mL (64.02 mM) ; Ethanol:30 mg/mL (38.41 mM)

Smiles

[H][C@@]12CC (C) (C) CC[C@@]11CO[C@@]22C=C[C@]3 ([H]) [C@@]4 (C) CC[C@H] (O[C@]5 ([H]) O[C@H] (C) [C@H] (O) [C@H] (O[C@]6 ([H]) O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]6O) [C@H]5O) [C@@] (C) (CO) [C@]4 ([H]) CC[C@@]3 (C) [C@]2 (C) C[C@@H]1O

Molecular Formula

C42H68O13

Molecular Weight

780.98

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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