KD-026
KD-026 (SLx-4090) is a potent and selective microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 8.0 nM. This small molecule is utilized in preclinical research for type 2 diabetes, investigating mechanisms related to lipid metabolism and chylomicron production in both in vitro and in vivo models.
Product Specifications
CAS Number
913541-47-6
Product Name Alternative
Inhibitor, enterocytic-specific, inhibit, MTP inhibitor, MTP, KD026, KD-026, KD 026, microsomal triglyceride transfer protein, dyslipidemia, SLx4090, SLx-4090, SLx 4090
Field of Research
Metabolism Research, Protein Biochemistry
Purity
99.73% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.66 mM) ; DMSO:55 mg/mL (100.63 mM)
Smiles
COc1cccc (C (=O) Nc2ccc3CN (CCc3c2) C (=O) Oc2ccccc2) c1-c1ccc (cc1) C (F) (F) F
Molecular Formula
C31H25F3N2O4
Molecular Weight
546.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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