Methotrexate metabolite
DAMPA (7-hydroxymethotrexate) is the primary active metabolite of the antifolate chemotherapeutic and immunosuppressant Methotrexate. It is widely used in pharmacological research to study drug metabolism, mechanisms of action, and resistance in both in vitro and in vivo cancer and autoimmune disease models.
Product Specifications
CAS Number
19741-14-1
Product Name Alternative
Drug Metabolite, DrugMetabolite, DAMPA, Antifolate, Methotrexate metabolite, Inhibitor, inhibit
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
95.28% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.07 mM) ; DMSO:4 mg/mL (12.3 mM)
Smiles
CN (Cc1cnc2nc (N) nc (N) c2n1) c1ccc (cc1) C (O) =O
Molecular Formula
C15H15N7O2
Molecular Weight
325.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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