MF-438
MF-438 is a potent and orally bioavailable small molecule inhibitor of stearoyl-CoA desaturase 1 (SCD1), demonstrating an EC50 of 2.3 nM against the rat enzyme. This tool compound is widely used in metabolic disease, cancer, and lipid metabolism research, enabling the investigation of SCD1 function in both cellular and animal models.
Product Specifications
CAS Number
921605-87-0
Product Name Alternative
MF438, MF-438, MF 438, inhibit, Inhibitor, rSCD1, SCD, StearoylCoA Desaturase (SCD), Stearoyl-CoA Desaturase, StearoylCoADesaturase (SCD), StearoylCoADesaturase, Stearoyl-CoA Desaturase (SCD)
Field of Research
Cancer Biology, Neuroscience
Purity
>98%
Bioactivity
SCD1 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 2 mg/ml with warming) .
Smiles
Cc1nnc (s1) -c1ccc (nn1) N1CCC (CC1) Oc1ccccc1C (F) (F) F
Molecular Formula
C19H18F3N5OS
Molecular Weight
421.44
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-Methyl-5- (6- (4- (2-trifluoromethyl) phenoxy) piperidin-3-yl) -1,3,4-thiadiazole
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