MI-538
MI-538 is a potent small molecule inhibitor that disrupts the menin-MLL fusion protein interaction with an IC50 of 21 nM. It is a valuable research tool for studying oncogenic mechanisms and has demonstrated activity in cellular assays and in vivo models of MLL-rearranged leukemia.
Product Specifications
CAS Number
1857417-10-7
Product Name Alternative
MI538, MI-538, MI 538, inhibit, Epigenetic Reader Domain, EpigeneticReaderDomain, HistoneMethyltransferase, Histone Methyltransferase, menin, menin and MLL interaction, Menin-MLL, Inhibitor
Field of Research
Epigenetics & Chromatin
Purity
99.31% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (17.65 mM) ; DMSO:95 mg/mL (167.67 mM)
Smiles
Oc1cc2n (Cc3cn[nH]c3) c (cc2cc1CN1CCC (CC1) Nc1ncnc2sc (CC (F) (F) F) cc12) C#N
Molecular Formula
C27H25F3N8OS
Molecular Weight
566.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6212271-01 0.1 mL
LAMP2 (Lysosome-associated Membrane Glycoprotein 2, LAMP-2, Lysosome-associated Membrane Protein 2, CD107 Antigen-like Family Member B, CD107b) (MaxLight 550)
Sign In for Pricing
View Details