MI-538
MI-538 is a potent small molecule inhibitor that disrupts the menin-MLL fusion protein interaction with an IC50 of 21 nM. It is a valuable research tool for studying oncogenic mechanisms and has demonstrated activity in cellular assays and in vivo models of MLL-rearranged leukemia.
Product Specifications
CAS Number
1857417-10-7
Product Name Alternative
MI538, MI-538, MI 538, inhibit, Epigenetic Reader Domain, EpigeneticReaderDomain, HistoneMethyltransferase, Histone Methyltransferase, menin, menin and MLL interaction, Menin-MLL, Inhibitor
Field of Research
Epigenetics & Chromatin
Purity
99.31% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (17.65 mM) ; DMSO:95 mg/mL (167.67 mM)
Smiles
Oc1cc2n (Cc3cn[nH]c3) c (cc2cc1CN1CCC (CC1) Nc1ncnc2sc (CC (F) (F) F) cc12) C#N
Molecular Formula
C27H25F3N8OS
Molecular Weight
566.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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