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Filorexant

Filorexant (MK-6096) is a potent, selective, and orally bioavailable dual antagonist of orexin receptors OX1 and OX2, with sub-nanomolar binding affinity. It is a valuable research tool for investigating sleep disorders and has been utilized in both in vitro binding assays and in vivo preclinical models of insomnia.

Product Specifications

CAS Number

1088991-73-4

Product Name Alternative

HCRT Receptor, Filorexant, Hypocretin Receptor, MK 6096, MK6096, MK-6096, Orexin receptor, Orexin Receptor (OX Receptor), OXReceptor, OX1, OX Receptor, OX2, Inhibitor, inhibit

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.88% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.51 mM) ; DMSO:100 mg/mL (237.82 mM)

Smiles

C[C@@H]1CC[C@@H] (COc2ccc (F) cn2) CN1C (=O) c1cc (C) ccc1-c1ncccn1

Molecular Formula

C24H25FN4O2

Molecular Weight

420.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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